Current Projects
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Alligator genome The American alligator is an important an interesting species for several reasons. Like in other reptiles, sex determination is not under genetic control. Rather, it is determined by the temperature at which embryonic development occurs. This development is particularly sensitive to environmental pollution. With collaborators, Dan Janes, Scott Edwards, Lou Guillette, Satomi Kohno, and Jeremy Sanford, we are investigating the early stages of sex differentiation in the American alligator. To assist this effort, we are sequencing and assembling the alligator genome. |
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Short-read sequence assembly We are actively involved in development of new methods for generating and evaluating assemblies of high-throughput sequence data. Application of these methods runs the gamut from bacterial genome sequence, in collaboration with Roger Linington's lab, to several vertebrate genome assembly and analysis projects. |
| Detecting and interpreting positive selection in recent human evolution | |
| Using RNAseq to understand the causes, consequences, and evolution of alternative splicing |
